Research
Research lines:
Biochemistry: molecular structures, biochemical mechanisms and biomedical applications
- The damage can be induced by the structural modification of the peptide/protein by reactive oxygen species (ROS) and other radicalar species, or by cross-linking reactions between peptide/protein and the oxidation products of other biomolecules (lipids, phospholipids, and DNA bases). We have been working on the development of mass spectrometry methods to allow the identification at biological levels, of radical oxidation products using mass spectrometry. In order to achieve this objective we have been analysing by mass spectrometry spin adducts and other oxidation products formed by the oxidation of amino acids and peptides.
Lipidomics Lab
- The Lipidomics research group has pioneered lipidomics in Portugal and, over the last two decades, leads the only national research group performing lipid analysis regularly. The team knowledge embraces multidisciplinary backgrounds, like chemistry, biochemistry, biotechnology, pharmaceutical sciences, and clinical areas with extensive experience in research projects through cutting edge mass spectral analysis. Our group has an extensive network of collaborators in several Universities and Research Institutes and companies worldwide. The team has published over 300 papers in international indexed journals with peer review.
Proteomics Lab
- Development of proteomics methodologies with biomedical applications
Metabolomics Lab
- Development of metabolomics methodologies with biomedical applications
